This conference brings together scientists from multidisciplinary fields employing different research strategies: (1) Epigenetic profiling at genome-wide and/or single cell level to identify complex dynamic regulatory interactions, (2) Bioinformatics and mathematical modelling to understand and predict observed (dynamic) phenotypic responses, (3) Innovative epigenetic interference tools using for instance CRISPR/dCas-based epigenetic editing tools to locally overwrite epigenetic signatures and to verify the impact of defined alterations in epigenetic regulation. The meeting provides a platform for scientists focusing on fundamental and biomedical research, clinicians and private sector scientists.
The Systems Epigenetics: Towards Precision Cancer Medicine Conference is organized in the context of the EpiPredict EU H2020 Innovative Training Network (www.EpiPredict.eu) coordinated by Dr Pernette Verschure. EpiPredict employs a systems medicine approach to obtain a detailed mechanistic understanding of epigenetic regulation in resistance development against hormonal treatment in breast cancer estrogen receptor positive patients.
On behalf of the organising committee
Dr Pernette J. Verschure (University of Amsterdam)